Apathyischaracterizedbylossofmotivation,decreasedinitiative,andemotionalblunting.Itishighlyprevalentinneurological,andpsychiatricdisorderslikeAlzheimer’sdisease,traumaticbraininjury,schizophrenia,Parkinson’sdisease,Huntington’sdisease,cerebrovasculardisorders,andmildbehaviouralimpairment.Ithasnegativeoutcomesincludingimpairmentsinactivitiesofdailyliving,caregiverburden,andhigherratesofinstitutionalizationandmortality.Thedefinitionofapathyhaschangedovertheyearsalongsidethedevelopmentofdiagnosticcriteriaandapathyscalesandmeasurements.Apathyisemergingasatreatmenttargetwithinterestinpharmacological,non-pharmacological,andneuromodulatorytreatmentsforapathy.Thereisalsoanincreasedunderstandingoftheneurobiologyofapathywithfunctionalandstructuralneuroimagingresearchstudies.Thisbookisacomprehensive,in-depthreviewfromexpertsinneurologyandpsychiatry.Itreviewsthecurrentstateofapathyinthesevariousdisorderswhilealsosummarizingapathydiagnosticcriteria,scalesandmeasurements,neuropathology,andtreatments.
Parkinson’sdisease NON PARKINSON schizophrenia
